Saudi News Saudi News – Riyadh: A study: a cheap antidepressant drug may reduce the severity of the Corona virus disease Source of the news – Saudi Arabia – cnn with news details A study: a cheap antidepressant drug may reduce the severity of the Corona virus disease:
Dubai, United Arab Emirates (CNN) – Researchers have discovered that an inexpensive and easy-to-obtain antidepressant drug can reduce the severe risk of infection with “Covid-19” by 33.33% in people exposed to it. at great risk.
A pilot study conducted in Brazil, which included 1,500 patients who were given this drug known as “fluvoxamine”, showed that the disease did not develop for them to reach the “severe” level, forcing them to be hospitalized.
This brand-name drug, Luvox, is a selective serotonin reuptake inhibitor (SSRI) that doctors prescribe for people with obsessive-compulsive disorder (OCD) and depression. But it can affect the development of inflammation, according to Dr. Angela Riesen, assistant professor of psychology at Washington University in St. Louis, who was involved in the study published in The Lancet Global Health.
“Fluvoxamine may reduce the production of inflammatory cytokine molecules, which may be caused by Sars-Cov-2 infection,” Riesen said in a published statement. It may also reduce the number of platelets that lead to blood clots due to infection with the Corona virus.
Riesen and her colleagues gave 741 volunteers with COVID-19 100 milligrams of fluvoxamine twice a day for 10 days, while the other 765 patients were given a placebo.
And 79 people (11%) in the group that received the depressive reserve medication needed to go to the emergency or hospitalization, compared to about 16% among those who received the placebo. That is, the first group recorded an overall risk rate of 5% less than the second group, and a lower relative risk rate of 32%.
To find out if this cheap drug should be added to the list of treatments given to patients with the Corona virus, more studies must be conducted in this regard. “The ten-day treatment costs $4 in well-resourced settings,” the researchers wrote. They note that it is not a cure, but if this drug can keep patients out of the hospital, it may be useful.
“Given the safety, tolerability and ease of use of fluvoxamine, as well as its low price and widespread reach, these findings may influence national and international trends for the clinical management of COVID-19,” the researchers concluded.
They pointed out that the study is not ideal, because it was conducted in Brazil, where the rate of hospitalization of patients was higher than that of patients with coronavirus in other clinical trials.
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