Dubai, United Arab Emirates (CNN) — People with certain health conditions that make them moderately or severely immunocompromised may receive a fourth dose of the COVID-19 vaccines, according to guidelines. Updated from the US Centers for Disease Control and Control.
And the US Centers for Disease Control and Control granted permission to give a third dose to some immunocompromised people aged 18 and over last August.
She said a third dose, rather than a booster, is necessary for people with low immunity, who may not have had a full immune response after the first two doses.
A study from Johns Hopkins University this summer showed that immunocompromised people were 485 times more likely to end up in hospital or die from Covid-19 than the majority of vaccinated people.
In smaller-scale studies, the US Centers for Disease Control and Prevention noted that fully vaccinated immunocompromised people accounted for about 44% of advanced cases requiring hospitalization.
And people with immunodeficiency are the most vulnerable group to transmit the virus to people in contact with them.
The US Food and Drug Administration has also authorized giving booster doses of the three vaccines available in America to some groups of people, which will include people with low immunity.
Research has revealed that giving a booster dose increases the antibody response to the vaccine in some immunocompromised people.
Currently, the Centers for Disease Control does not have a recommendation for the fourth dose of the vaccine, and urges people who are immunocompromised to consult their physicians to determine if a fourth dose is necessary.
The category of people with moderate to severe immunodeficiency includes both those undergoing active cancer treatment for leukemia or tumors, certain organ transplants, people who have received stem cells, people with advanced or untreated HIV, and those taking high doses. of corticosteroids or other medicines that can suppress their immune system.
The Centers for Disease Control estimates that about 9 million people living in the United States, or about 2% of the population, fall into this category.
People with low immunity who have received a single dose of the Johnson & Johnson vaccine should get a booster dose at least two months after receiving the vaccine.
The CDC notes that people who choose to receive a booster dose of Moderna, even if they receive a different vaccine for the first two doses, must receive half the authorized dose of Moderna.